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This paper reviews the problems of passive immunization of rabies. In the Russian Federation remains serious epizoot-epidemiological situation of rabies, characterized the increase of the number of disadvantaged settlements and the registration of the hydrophobia in the population. In these circumstances the only possibility to prevent the disease in humans who suffered from the bite of a rabid animal, is timely and appropriate the administration of modern anti-rabies drugs.doi:10.31631/2073-3046-2015-14-5-85-89 fatcat:xk7o3orpqvb4vdar6y7ln5xiim