A copy of this work was available on the public web and has been preserved in the Wayback Machine. The capture dates from 2017; you can also visit the original URL.
The file type is
Mammalian target of rapamycin (mTOR) plays a major role in the regulation of protein translation, cell growth, and metabolism. Three basic signalling pathways that have been described as important in cancer including the phosphatidylinositol 3-kinase (PI3K)/AKT/mTOR kinase cascade, the protein kinase C (PKC) family, and the mitogen-activated protein kinase (MAPK)/Ras signalling cascades. mTOR has been defined as a key kinase acting downstream of the activation of PI3K/AKT. These pathways aredoi:10.5798/diclemedj.0921.2013.01.0248 fatcat:gykwts7ws5g6necobv4wnyli5u