Principles of gene therapy

Biju Mammen, T Ramakrishnan, Uma Sudhakar, Vijayalakshmi
2007 Indian Journal of Dental Research  
Genes are specific sequences of bases that encode instructions to make proteins. When genes are altered so that encoded proteins are unable to carry out their normal functions, genetic disorders can result. Gene therapy is designed to introduce genetic material into cells to compensate for abnormal genes or to make a beneficial protein. This article reviews the fundamentals in gene therapy and its various modes of administration with an insight into the role of gene therapy in Periodontics and
more » ... n Periodontics and future percepts and the technical and ethical issues of using gene therapy.
doi:10.4103/0970-9290.35832 fatcat:izxzipoup5czpdui5gztdvq67e