Treatment of Vitamin D Deficiency in Children and Adolescents

Arani KS, Tehrani FM, Rezvani RS
2016 Journal of Nutrition and Health Sciences  
Material and Method: In this clinical trial 100 children and adolescents with vitamin D deficiency or insufficiency were participated. The vitamin D deficiency defined as 25OHD ≤ 15 ng/ml and vitamin D insufficiency as 15 ≤ 25OHD ≤ 20 ng/ml. In terms of obesity, individuals were classified in two groups: obese & overweight (57 subjects) and normal weight (43 subjects). All subjects received 50000 IU vitamin D once a week for 6 weeks, and the 25OHD level was measured 2-6 months later. Result:
more » ... mean 25OHD level before treatment in first group (obese & overweight) was 10.74±5.96 ng/ml and in normal weight group was10.81±5.41 ng/ml. (P=0.54) Average levels of 25OHD after initial treatment was 33.64±22.43 ng/ml and 37.66±17.74 ng/ml respectively (P=0.6) The frequency of vitamin D deficiency and insufficiency after initial treatment was 12.8% and 9.3% respectively. Conclusions: This study showed that treatment with 50000 IU Vitamin D weekly for 6 week is a safe and effective regimen for majority of Vitamin D deficient or insufficient children regardless of obesity status.
doi:10.15744/2393-9060.3.105 fatcat:o3ks4u66qra53idn2flnhuwlx4