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N-Stearoylethanolamine (NSe) is a minor lipid that belongs to the N-acylethanolamines family that mediates a wide range of biological processes. The effect of the NSE on reactive oxygen species (ROS) production and NF-κB activation stimulated by lipopolysaccharide (LPS) in rat peritoneal macrophages (PM) was evaluated. PM were obtained from the rat peritoneal cavity. roS were detected following dCFdA and DHE fluorescence. Nuclear translocation of p65 NF-κB was examined by immunofluorescentdoi:10.15407/ubj89.05.062 fatcat:ptjv6ibjs5hdrpvtrakvc6fm2a