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Natural products play a dominant role in the development of novel drug leads for the treatment and prevention of diseases. Toxicity is an expression of being poisonous, indicating the state of adverse effects led by the interaction between toxicants and cells. This interaction may vary depending on the chemical properties of the toxicants and the cell membrane. Hence, evaluation of toxic properties of a substance is crucial when considering for public health protection. Protease inhibitorsdoi:10.1080/23312025.2016.1191588 fatcat:mdj2kme6yvdwdj3gzrff7zwoom