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The fate of the broad-host-range, conjugative plasmid pAMPl in the digestive tract of mice was monitored by DNA-DNA hybridisations using a probe containing the ermAM determinant (macrolide-lincosamide-streptogramin type B resistance). Transfer of pAMPl from Lactobacillus reuteri to Enterococcus faecium occurred in the digestive tract of infant mice and from E. faecium to E.faecalis and to L. ferrnentum in the adult intestinal tract. Long-term administration of lincomycin to the animals resulteddoi:10.3402/mehd.v4i6.7723 fatcat:hatnoafwvbfjrh2kxbgsziyori