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Nanoscale Nonlinear Dynamic Characterization of the Neuron-Electrode Junction
2008
Journal of Computational and Theoretical Nanoscience
Extracellular recordings from neurons using microelectrode and field effect transistor arrays suffer from many problems including low signal to noise ratio, signal attenuation due to counter-ion diffusion from the bulk extracellular medium and a modification of the shape of the cell-generated potentials due to the presence of a highly dispersive dielectric medium in the cell-electrode cleft. Attempts to date to study the neuron-electrode interface have focused on point or area contact
doi:10.1166/jctn.2008.1114
pmid:20204183
pmcid:PMC2831233
fatcat:nkjsrstuljfnzgmbuhzqv3ybyq