Type of article: Research article "Association of ABO blood groups with craniofacial morphology among orthodontic patients of Kathmandu district" [post]

2019 unpublished
The craniofacial morphology and blood groups both are related to genetic components, hence it can be hypothesized that blood groups have an association with craniofacial morphology. Some studies showed the relationship whereas others could not find any relationship that may be due to geographic diversity of the population. The aim of this study was to find out the relationship between ABO blood groups and craniofacial morphology among orthodontic patients of Kathmandu district. Materials and
more » ... t. Materials and Methods: In this cross sectional study, a total of 385 participants (age range from 13-45 years) were selected among the orthodontic patients who came for orthodontic treatment in private orthodontic clinics. After obtaining written consent, all the patient's demographic information were recorded and lateral cephalograms were obtained from the patient's record. Blood group of all the participants was recorded. Results: The study found that among the total of 385 participants, 162 (42.07%) were male while 223 (57.93%) were female and the mean age was 16.31±4.38 years. Twenty cephalometric parameters depicting craniofacial morphology were digitally analyzed using lateral cephalogram. The prevalence of blood group O patients was highest (32.20%) followed by blood group B (30.64%), blood group A (29.88%) and blood group AB (7.28%). Statistical analysis with one way ANOVA was used for association of numerical data and blood groups that revealed nine out of twenty cephalometric parameters were statistically significant among different blood groups (p<0.05). Tukey post hoc test was done to find out where the significant difference occurs among the groups. Conclusions: The evaluation of the relationship between blood group and craniofacial morphology revealed that blood groups have association with some craniofacial parameters. This suggest, there may be some genetic influence of ABO blood group on craniofacial morphology.
doi:10.21203/rs.2.14839/v1 fatcat:mjmorbmplzculi4iw5t7q4hldm