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Adipose tissue as an endocrine modulator: Hormonal changes associated with obesity Adipose tissue not only stores fat, but secretes factors and hormones, which modify the regulation, metabolism and secretion of several other hormones. The objective of this review is to describe the hormonal disorders associated with increased adipose tissue, which acts as a modulator or disruptor of the endocrine physiology, with special reference to cortisol, androgens, growth hormone and thyroid axis, anddoi:10.4067/s0034-98872010001100015 fatcat:73d62aoznbf5llqtqr6c6xkvua