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Non-small cell lung cancer (NSCLC) is a leading cause of cancer related mortality. Main factors of development of NSCLC are many immune cells involved in tumor microenvironment. Infiltration with CD68 positive tumor associated macrophages (TAM) in the tumor stroma or in the tumor islets is associated with prognosis and stage of the disease for a long time. Investigating immunohistochemically 40 patients with NSCLC we discovered that 25% of patients with metastasis in lymph nodes had lowdoi:10.15547/tjs.2018.03.010 fatcat:rzwiua4gizea7ig2562zi3vje4