Smita Das, Chakravarty B P
2016 Journal of Evolution of Medical and Dental Sciences  
BACKGROUND Anaemia is frequently associated with hypothyroidism. This study was conducted to study the prevalence and types of anaemia in primary hypothyroidism along with its various clinical manifestations. METHODS In this retrospective study, out of the 120 patients with primary hypothyroidism, 50 that were found to be suffering from anaemia were evaluated for the type most prevalently associated with hypothyroidism considering various clinical manifestations and laboratory investigations.
more » ... y investigations. This was carried out in a tertiary care teaching hospital. RESULTS Among 120 patients, 50 were detected to have anaemia with a prevalence of 41.66% [95% Confidence Interval: 0.32-0.51]. Of whom 44 were females (51.11%) and 6 males (17.64%). 23 (46%) patients had normocytic normochromic anaemia, 19 (38%) patients had microcytic hypochromic anaemia and 8 (16%) patients had macrocytic anaemia. The most common clinical symptoms suggestive of anaemia in hypothyroidism were easy fatigability (100%). Pallor was seen in all 50 patients (100%). The mean Hb level in the study group was 7.34 g/dL with a range 6.2-8.5 g/dL. The mean reticulocyte count (Corrected) was found to be 0.92% in all types of anaemia. The mean S. ferritin level was found to be low (11.45 mcg/dL) only in those with microcytic hypochromic anaemia. The study revealed 3 patterns of bone marrow picture namely normocellular, erythroid hyperplasia and hypercellular marrow. CONCLUSIONS Anaemia in hypothyroidism is a common association and most commonly presented with easy fatigability and decreased appetite. Normocytic normochromic anaemia constituted the most common type of anaemia in hypothyroidism.
doi:10.14260/jemds/2016/499 fatcat:onuvsqoxb5csrn56i74ukyqbla