Integration of a Nanoporous Platinum Thin Film into a Microfluidic System for Non-enzymatic Electrochemical Glucose Sensing

Segyeong JOO, Sejin PARK, Taek Dong CHUNG, Hee Chan KIM
2007 Analytical Sciences  
In this paper, we describe an amperometric-type enzymeless glucose sensing system based on a nanoporous platinum (Pt) electrode embedded in a microfluidic chip. This microchip system is comprised of a microfluidic transport channel network and a miniaturized electrochemical cell for nonenzymatic glucose sensing. Sample and buffer solutions were transferred to the cell by programmed electroosmotic flow (EOF). A nanoporous Pt electrode with the roughness factor of 200.6 was utilized to determine
more » ... lized to determine glucose concentrations in phosphate buffered saline (PBS) by the direct oxidation of glucose, without any separation process. The sensitivity of the developed system is 1.65 μA cm -2 mM -1 in the glucose concentration range from 1 -10 mM in PBS.
doi:10.2116/analsci.23.277 pmid:17372368 fatcat:uqr7dsditnhinodngctsoq64ku