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Investigating childhood maltreatment as a modifier of genetic risk for cardiovascular disease in the UK Biobank
[article]
2022
medRxiv
pre-print
Cardiovascular disease (CVD) is influenced by genetic and environmental factors. Childhood maltreatment is associated with CVD and may modify genetic susceptibility to cardiovascular risk factors. We used genetic and phenotypic data from 100,833 White British UK Biobank participants (57% female; mean age = 55.9 years). We regressed nine cardiovascular risk factors/diseases (alcohol consumption, body mass index [BMI], low-density lipoprotein cholesterol, lifetime smoking behaviour, systolic
doi:10.1101/2022.01.26.22269809
fatcat:qtdxkrmzjfa2nbnz5tdbcq7cni