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common factor is still hidden and promises to remain so until further chemical research opens the door to a more complete understanding of metabolism. Acetone alone I believe to be an insufficient cause of this condition. Other substances seem to appear progressively with an increase in the severity of the symptoms: first, diacetic acid; then, beta-oxybutyric acid, and it is possible that in the near future other fatty acids will be detected. Be that as it may, acetone should be well regardeddoi:10.1056/nejm190807091590206 fatcat:klny4g26jfbevbkgyhm6rdhydi