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The study was undertaken to evaluate the antihyperglycemic potential of mangiferin purified from methanolic root extract of Salacia chinensis (S. chinensis) in control and streptozotocin (STZ)-induced diabetic rats. The mangiferin was administered orally at a dose of 40 mg/kg weight per day (30 days) to STZ-induced diabetic rats. The mangiferin treated diabetic rats significantly decreased the level of blood glucose, glycosylated hemoglobin as well as increased level of insulin and hemoglobin.doi:10.1248/jhs.55.206 fatcat:asdur54ptjb2rb6oqhr3wqjp4y