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In this study, we examined the effect of a hot-water extract of coccolithophore Pleurochrysis carterae on melanogenesis in B16F1 and B16F10 melanoma cells. P. carterae extract inhibited the α-melanocyte-stimulating hormone (α-MSH)-enhanced melanin synthesis in B16F1 melanoma cells. P. carterae also inhibited unstimulated melanin synthesis in B16F10 melanoma cells. Western blotting showed that the P. carterae extract inhibited tyrosinase and microphthalmia-associated transcription factor (MITF)doi:10.3390/cosmetics6040060 fatcat:harse4vjknfard655m4m2wotoa