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A cell-extrinsic ligand acquired by activated T cells in lymph node can bridge L-selectin and P-selectin
2018
PLoS ONE
P-selectin expressed on activated endothelia and platelets supports recruitment of leukocytes expressing P-selectin ligand to sites of inflammation. While monitoring P-selectin ligand expression on activated CD8 + T cells in murine adoptive transfer models, we observed two distinct ligands on responding donor cells, the canonical cell-intrinsic P-selectin ligand PSGL-1 and a second undocumented P-selectin ligand we provisionally named PSL2. PSL2 is unusual among selectin ligands in that it is
doi:10.1371/journal.pone.0205685
fatcat:rbz75kdz4fbeffacihmgwdeyh4