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Amyloidosis is a group of disorders characterized by extracellular deposition of a proteinaceous homogenous eosinophilic hyaline substance known as amyloid. Congo red staining is a specific stain for amyloid which shows an apple-green birefringence on polarized microscopy. Amyloid deposition can be systemic or localized. Primary amyloidosis (also known as AL amyloidosis) is the most common form of amyloidosis characterized by generalized deposition of excess immunoglobulin light chains. It isdoi:10.32677/ijcr.2019.v05.i02.031 fatcat:6333dw2wtzfcja5x6c3kiv3ise