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The evolution of modularity in bacterial metabolic networks
2008
Proceedings of the National Academy of Sciences of the United States of America
Deciphering the modular organization of metabolic networks and understanding how modularity evolves have attracted tremendous interest in recent years. Here, we present a comprehensive large scale characterization of modularity across the bacterial tree of life, systematically quantifying the modularity of the metabolic networks of >300 bacterial species. Three main determinants of metabolic network modularity are identified. First, network size is an important topological determinant of
doi:10.1073/pnas.0712149105
pmid:18460604
pmcid:PMC2383979
fatcat:awkppmfdyfb2jk2ubsj24gnkq4