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Clinical pharmacokinetic profiles were investigated following intramuscular (i.m.) administration to pigs with a commercial tylosin-florfenicol combination product at a dose of 2.5 mg/kg tylosin and 5 mg/kg florfenicol or 10 mg/kg tylosin and 20 mg/kg florfenicol. The quantitation limit (QL) of florfenicol was 0.1 µg/ml, the inter-day and intra-day precision (CV%) were both beow 10%. The quantitation limit (QL) of tylosin was 0.05 µg/mL. The pharmacokinetic characteristics after i.m. doses weredoi:10.1292/jvms.70.99 pmid:18250580 fatcat:xyhtkjzupbhp3kzniaetvrkt2y