Prevalence of Genital Chlamydia Trachomatis among Pregnant Women in a Northwestern Teaching Hospital, Nigeria [post]

Rabi'at Aliyu Muhammad, Adebiyi Gbadebo Adesiyun, Shafaatu Ismail Sada, Shamsudin Aliyu, Abdulhakeem Abayomi Olorukooba
2020 unpublished
Background: Chlamydia trachomatis (Ct) is now being considered as an "obstetric pathogen" due to its potential in causing adverse pregnancy and perinatal outcomes. Consequent to being the commonest bacterial sexually transmitted infection, screening is recommended at the initial visit of antenatal care, but few countries have routine pregnancy screening and treatment programs. Prevalence assessment is a core component of the World Health Organisation sexually transmitted infection -surveillance
more » ... ction -surveillance programming which enables a country to monitor trends of this infection, for appropriate implementation of preventive measures. Aim: To determine the prevalence of Ct infection among pregnant women, and to describe sociodemographic characteristics and reproductive profile of seropositive pregnant women attending the antenatal clinic of Ahmadu Bello University Teaching Hospital, Zaria. Methods: Socio-demographic characteristics and risk factors were sought from 90 pregnant women using a proforma. Their sera were assayed for the presence of Ct immunoglobulin G (IgG) using ELISA. Data were analysed using SPSS version 21. Categorical variables were represented using frequency and percentages while associations between categorical variables were determined using Fisher's exact test with p < 0.05 considered significant. Results: Prevalence of Ct infection was found to be 3.3% (3/90). The mean age of infected women was 34.3 ± 4.6 years. All seropositive women were gainfully employed and had tertiary education. Mean parity was 3, the majority (2/3,66.7%) had no previous miscarriage and none had a history of prior stillbirth.Conclusion: The prevalence of Ct in this study is low compared to the pooled prevalence for the West African sub-region. A broader community-based study using a nucleic acid amplification technique is suggested.
doi:10.21203/rs.3.rs-97747/v1 fatcat:fndtaxunjbgopicy3xflwnuqqu