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Calcium pumps and channels modulate cell proliferation and apoptosis by regulating intracellular calcium (Ca2 þ). The plasma membrane Ca2þ ATPase isoform, PMCA2, is a calcium efflux mechanism that extrudes Ca2 þ from the cytosol into the extracellular space. PMCA2 hasdoi:10.1016/j.nhtm.2014.11.043 fatcat:2kdzai7q5va6xpzm27qct5t3w4