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Liver diseases are among the public health concerns that significantly contribute to the global burden of mortality and illness. Herbal medicines are always used to treat a great number of diseases such as hepatotoxicity worldwide. Objectives: The current study aimed at investigating the hepatoprotective activity of microemulsion (ME)-based system Prunus cerasus kernel extract against carbon tetrachloride (CCL4)-induced hepatic injury in mice. Methods: In the current experimental study, 56 maledoi:10.5812/jjnpp.14282 fatcat:xbgxlw43ajhz7c4cdtz53p3bp4