Validation of Antimicrobial and Anti-inflammatory Activities in Chondrococcus hornemanni and Pocockiella variegata

Maria Catherrine. T
2019 International Journal for Research in Applied Science and Engineering Technology  
In this article the study on validation of the bioactive principles and its efficacy (antibacterial and antifungal) and anti inflammatory activity was done with the solvent extract of two different groups of algae that is, Chondrococcus hornemanni and Pocockiella variegata. The extract was prepared using solvents such as aqueous, hexane, chloroform and chloroform: methanol(2:1) mixture. The extracted sample was tested in vitro for their antimicrobial activities against different types of
more » ... ent types of bacteria using disc diffusion method. Chloroform extract of Pocockiella against Bacillus subtilis and Chondrococcus against Psedomonas aeruginosa showed maximum inhibitory zone than other solvents. Antifungal activity was done using poisoned food method in which no significant antifungal activity was observed in all the extracts. The determination of anti inflammatory activity was done using SRBC method and characterized under UV -VIS spectrophotometer under 560nm, where the maximum inhibitionof 52% was observed in 400mg/ml of chloroform: methanol extract of Chondrococcus.
doi:10.22214/ijraset.2019.4018 fatcat:swefc6e3uffp3pq54u43mf77fm