Pepsine Wine'a New Preparation

J C Reeve
1865 American Journal of the Medical Sciences  
1865.] Reeve, Pepsine Wine. 55 But in this I consider quinia one of the best cholagogues we have, not immediately, but secondarily. In every case, as soon as the fever was broken up, all the secretions, including that of the liver, at once commenced to flow. My first case occurred in the mountains, where the weather is always cool, remote from any malarious district, and was very prevalent in 1859, the first year of my Territorial residence, and practitioners of that early day informed me that
more » ... y informed me that it could not be cut short, though they acknowledged they never pushed quinia beyond an ordinary dose. By the time I met my first case (narrated above) it had become very rare in that region. Doubtless it depended at an early day on the exposure and insufficient diet of our mining community, and, I think, would have yielded to large doses of quinia (from sixty to eighty grains), if any one had had the nerve to administer it.
doi:10.1097/00000441-186507000-00004 fatcat:v63ut5clqfag3ppefh2zctcp6q