FeCl3/SiO2 NPs as a robust and efficient catalyst for the synthesis of 2-aryl-5-methyl-2,3-dihydro-1H-3-pyrazolones

Esmaeil Afkhami, Javad Safaei-Ghomi
2016 Current Chemistry Letters  
A four-component reaction of phenylhydrazines, ethyl acetoacetate, aldehydes and β-naphthol has been achieved in the presence of FeCl3/SiO2 nanoparticles as a highly effective heterogeneous catalyst to produce 2-aryl-5-methyl-2,3-dihydro-1H-3-pyrazolones in good to excellent yields, short reaction times, mild reaction conditions and the employment of a costeffective catalyst.
doi:10.5267/j.ccl.2016.7.002 fatcat:z37xed7dkjauza4d4ero7ksc2q