Evasion Of Hepatic Tissue Damage Through Ameliorative Effect Of Flaxseed Oil: An Experimental Research On Albino Rats (Male)
Objective: Hepatic damage is created by Lipofundin which is used in parenteral therapies and is a soya-bean based lipid emulsion. This research was performed to know preventive effect of flaxseed oil on the hepatic damage. Material and Methods: Our research was of experimental nature conducted at Allied Hospital, Faisalabad (February, 16 to January, 17). This research is done to determine effect of the flaxseed oil on lipofundin induced (hepatotoxicity). From animal house, 32 male adult-albino
... male adult-albino rats were taken & classified in 4 equal groups. First group was control group & given (flaxseed oil) three ml per kg intraperitoneal on daily basis for ten days & only sacrificed on the 11th day. Second group B, Lipofundin three ml per kg intravenously on daily basis for ten days & only sacrificed on 11th day. Third group C, Lipofundin two ml per kg intravenously on daily basis for ten days & only sacrificed on 21st day. Fourth group D, Lipofundin two ml per kg intravenously for a period of ten days and also followed by (Flaxseed oil) three ml per kg intraperitoneal for a period ten days & only sacrificed on 21st day. Results: Hepatic tissue damage was found to be restored by flaxseed oil. This damage was caused by (Lipofundin administration). Conclusion: Hepatic tissue damage is caused by (Lipofundin Flaxseed oil) & Lipofundin. The flaxseed oil has an ameliorative effect on it. So by using it, we may avoid hepatic tissue damage which is caused by (Lipofundin) and is used for (parenteral therapies). Keywords: Lipofundin, Hepatotoxicity, Flaxseed oil.