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The production of ethanol from sugarcane or molasses generates vinasse, a residue rich in organic matter and minerals. Vinasse is often used in fertilization and irrigation practices, which may be linked to negative environmental outcomes if excess is applied. Herein, we introduce a novel alternative to the treatment of vinasse promoting the reduction in Chemical Oxygen Demand (COD) levels, phenolic compounds, and its mineral content through the coupling of ozone treatment, anaerobic digestion,doi:10.3390/environments6010005 fatcat:sepc2gjsirgklcrdexff6uszby