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5-Azacytidine affects the programming of expression of the somatic nucleus of Paramecium
1989
Development
This report introduces a new system in the study of programming of genomic function during development of the somatic nucleus of Paramecium tetraurelia. Previous works have established a definite, but replaceable, role of the germ nuclei (micronuclei) in oral development in the asexual cycle; their removal from the cell generates viable amicronucleate cell lines, which characteristically suffer a transient period of growth depression marked by abnormal oral development. Such cell lines
pmid:2482165
fatcat:5zzyqjuxqvbybozotxe4vwjkp4