Crouzon Syndrome: a fibroblast growth factor receptor 2 gene mutation

Farhad Safari, Kamran Mottaghi, Rofeideh Fallahinejadghajari, Masoud Nashibi
2017 Journal of Cellular & Molecular Anesthesia (JCMA)   unpublished
Crouzon syndrome is a rare autosomal dominant premature cranyosynostosis, caused by fibroblast growth factor receptor 2 gene mutation on chromosome 10. The predominant skull and facial malformations with potential compromised airway make the crouzon syndrome a demanding issue for anesthesiologists and surgeons, required dynamic team work. In this report we describe a child, a known case of Crouzon syndrome who was a candidate for optic nerve decompression through endoscopic surgery. The
more » ... urgery. The anesthetic considerations and management are presented.