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Can Clustal-style progressive pairwise alignment of multiple sequences be used in RNA secondary structure prediction?
2007
BMC Bioinformatics
In ribonucleic acid (RNA) molecules whose function depends on their final, folded three-dimensional shape (such as those in ribosomes or spliceosome complexes), the secondary structure, defined by the set of internal basepair interactions, is more consistently conserved than the primary structure, defined by the sequence of nucleotides. Results: The research presented here investigates the possibility of applying a progressive, pairwise approach to the alignment of multiple RNA sequences by
doi:10.1186/1471-2105-8-190
pmid:17559658
pmcid:PMC1904245
fatcat:nlmoqtusdfeexmmm2ugkuymiru