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In several species the epidermal growth factor (EGF) is known to be a potent mitogen which ensures the integrity of the gut mucosa. In the pig its role in the gut was not investigated. Antisera against recombinant porcine EGF were raised in rabbits. The antiserum was used to screen EGFimmunoreactivity in histological sections of the duodenum and jejunum of healthy piglets and piglets with diarrhoea. The specificity of the staining reaction was ensured. Immunoreactivity was found in all gobletdoi:10.22358/jafs/67986/2001 fatcat:bvtc7odirjajvpfnvs7f6doe5e