F-18 FDG PET/CT in pulmonary artery sarcoma: clinical vignette

Stjepan Hmelik, Margareta Dobrenić, Dražen Huić
2018 Nuclear Medicine Review  
showed extensive intraluminal mass in the pulmonary trunk and left pulmonary artery, diagnosed as massive pulmonary embolism. Since there was no clinical improvement after anticoagulant therapy, CT pulmonary angiography was repeated (Figure 1 ), and with no change observed in the intraluminal filling defect in pulmonary trunk, the possibility of tumor was raised. For further evaluation of a possible malignancy, F-18 FDG PET/CT was performed. It showed increased FDG uptake, suspicious for an
more » ... spicious for an aggressive tumor, in the intraluminal lesion of the pulmonary trunk and along the wall of the left pulmonary artery (Figure 2 ). There was no extrathoracic abnormality seen on PET/CT scan. Histopathological finding after complete pulmonary artery resection and left pneumonectomy showed a 9 cm long high grade undifferentiated pleomorphic sarcoma. No metastases were found in the parenchyma of the left lung. Three months after diagnosis, the patient was doing well and was receiving adjuvant chemotherapy treatment consisting of gemcitabine/docetaxel combination.
doi:10.5603/nmr.a2018.0011 pmid:29442347 fatcat:3365goxipnc2xjtmozuvk63ppe