Optical Neural Interfaces

Melissa R. Warden, Jessica A. Cardin, Karl Deisseroth
2014 Annual Review of Biomedical Engineering  
Genetically encoded optical actuators and indicators have changed the landscape of neuroscience, enabling targetable control and readout of specific components of intact neural circuits in behaving animals. Here, we review the development of optical neural interfaces, focusing on hardware designed for optical control of neural activity, integrated optical control and electrical readout, and optical readout of population and single-cell neural activity in freely moving mammals. 103 Annu. Rev.
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doi:10.1146/annurev-bioeng-071813-104733 pmid:25014785 pmcid:PMC4163158 fatcat:vpcuoauhn5gu7o2az54sqgr3ym