Initial infarct size predicts subsequent cardiac remodeling in the rat infarct model: an in vivo serial pinhole gated SPECT study

Fatiha Maskali, Philippe R Franken, Sylvain Poussier, Nguyen Tran, Chris Vanhove, Henri Boutley, Hervé Le Gall, Gilles Karcher, Faïez Zannad, Patrick Lacolley, Pierre Y Marie
2006 Journal of Nuclear Medicine  
The rat infarct model is widely used to study left ventricular (LV) remodeling, a main cause of heart failure characterized by progressive LV dilatation. Using pinhole collimators and advances in data processing, gated SPECT was recently adapted to image the rat heart. The aim of this study was to assess this new imaging technique for predicting and quantifying variable LV remodeling from the rat infarct model.
pmid:16455641 fatcat:zkzug5lzsfhfnmilh62k2ibjc4