Clinical features in mild type and severe type of COVID-19 patients [post]

Wenxiong Xu, Qiumin Luo, Dabiao Chen, Ziying Lei, Yuanli Chen, Juan Wang, Xuejun Li, Zhanlian Huang, Bingliang Lin, Zhiliang Gao, Jing Liu, Liang Peng
2020 unpublished
Background Coronavirus Disease 2019 (COVID-19) outbroke in Wuhan and spread to the world quickly. We aim to describe the clinical features and compare them between mild type and severe type of COVID-19 patients. Methods Laboratory confirmed COVID-19 patients were included in this study. Patients' demographic data and clinical data were recorded and compared between mild type and severe type. Results Fifteen patients were confirmed COVID-19 and enrolled in this study. Six patients were of mild
more » ... ents were of mild type, while 9 patients were of severe type. Statistical differences were found between mild type and severe type patients in retirement, epidemiological history, baseline blood level of lactate dehydrogenase and Oxygenation Index (All p < 0.05). All patients had ground-glass opacities without consolidation in initial chest computed tomography images, 2 (16.7%) patients had pulmonary nodules. There were no statistical differences between mild type and severe type patients in initial chest CT findings (All p > 0.05). Conclusions Differences can be found in baseline clinical features between mild type and severe type of COVID-19 patients to help health care providers making early judgement to the severity and proper treatment. Trial registration: The study was registered in ClinicalTrials.gov, NCT04279782. Registered 20 February 2020 - Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT04279782?term=NCT04279782&draw=2&rank=1
doi:10.21203/rs.3.rs-23499/v1 fatcat:kmty724nhngbtgk6mq2n7qydue