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MicroRNA-382 inhibits cell growth and migration in colorectal cancer by targeting SP1
2018
Biological Research
Emerging evidence showed that microRNAs (miRs) play critical roles in human cancers by functioning as either tumor suppressor or oncogene. MIR-382 was found to function as tumor suppressor in certain cancers. However, the role of MIR-382 in colorectal cancer (CRC) is largely unknown. Specificity protein 1 (SP1) is highly expressed in several cancers including CRC and is correlated with poor prognosis, but it is unclear whether or not MIR-382 can regulate the expression of SP1. MIR-382
doi:10.1186/s40659-018-0200-9
pmid:30474556
fatcat:rqdfia6s7zcq3ojc6cfrrr37dy