Prevalence of Thyroid Dysfunction in Diabetic Patients of Visakhapatnam District
Journal of Chemical and Pharmaceutical Sciences
The present study was designed to investigate the prevalence of thyroid dysfunction in patients with both type 1 and type 2 diabetes mellitus who attending outpatients department (OPD) of King George Hospital (KGH), Visakhapatnam. The population of 50 healthy volunteers and 200 diabetic patients attended OPD of KGH during September 2015 to September 2016. The age, sex, BMI and stress rate were noted. All the subjects were investigated for fasting blood glucose (FBS), glycosylated hemoglobin
... ated hemoglobin (HbA1c), lipid profile (total cholesterol, triglycerides, HDL, LDL and VLDL) and thyroid hormones (triidothyronine (T3), thyroxin (T4) and thyroid stimulating hormone (TSH)) were estimated. The incidence of thyroid dysfunction was also noted. The significant elevation of FBS, HbA1c, serum cholesterol, serum triglyceride, LDL levels and VLDL, lowered levels of HDL was observed in diabetic patients as compared to health volunteers. The level of T3 and T4 were not significantly altered while the level of TSH was significantly higher in diabetics as compared to healthy volunteers. The incidence of sub clinical hypothyroidism (25.3) was found to be more in type 2 DM patients compared to other states of thyroid dysfunction. The prevalence of thyroid dysfunction among type 2 DM patients is very high (25.3 %) with subclinical hypothyroidism is being most common. Continuous monitoring of thyroid hormones is important to control the prevalence of thyroid dysfunction in patients with type 2 diabetes mellitus.