A B S T R A C T Background Manipulation and mobilisation are often used, either alone or combined with other treatment approaches, to treat neck pain. Objectives To assess if manipulation or mobilisation improves pain, function/disability, patient satisfaction, quality of life, and global perceived effect in adults with acute/subacute/chronic neck pain with or without cervicogenic headache or radicular findings. Search methods CENTRAL (The Cochrane Library 2009, issue 3) and MEDLINE, EMBASE,

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... ual Alternative and Natural Therapy, CINAHL, and Index to Chiropractic Literature were updated to July 2009. Selection criteria Randomised controlled trials on manipulation or mobilisation. Data collection and analysis Two review authors independently selected studies, abstracted data, and assessed risk of bias. Pooled relative risk and standardised mean differences (SMD) were calculated. Main results We included 27 trials (1522 participants). Cervical Manipulation for subacute/chronic neck pain : Moderate quality evidence suggested manipulation and mobilisation produced similar effects on pain, function and patient satisfaction at intermediate-term follow-up. Low quality evidence showed manipulation alone compared to a control may provide short-term relief following one to four sessions (SMD pooled -0.90 (95%CI: -1.78