Serotypes, Antimicrobial Susceptibility, and Minimal Inhibitory Concentrations of Actionbacillus pleuropneumoniae Isolated from Slaughter Pigs in Taiwan (2002-2007)

Cheng-Yao YANG, Chao-Nan LIN, Chuen-Fu LIN, Tsung-Chou CHANG, Ming-Tang CHIOU
2011 Journal of Veterinary Medical Science  
In total, 211 isolates of A. pleuropneumoniae were collected from pigs with hemorrhagic pneumonia at slaughterhouses during 2002-2007. Serotypes, antimicrobial susceptibility and minimum inhibitory concentration (MIC) values were determined for each isolate of A. pleuropneumoniae to 10 antimicrobial agents. Serovar 1 of A. pleuropneumoniae was predominant in Taiwan in 138 of the 211 isolates, followed by serovars 2 and 5. More than 90% of collected isolates were sensitive to ceftiofur,
more » ... ceftiofur, cephalothin, and chloramphenical. However, lincospectin and gentamicin were relatively less susceptible with sensitivities of only 2.4 and 5.7%, respectively. Additionally, ceftiofur had the highest in vitro activity with an MIC 50 of 2.2 µg/ml, followed by cephalothin (2.7 µg/ml) and chloramphenicol (7.9 µg/ ml). Lincospectin had the least activity with MIC 50 and MIC 90 values of 73.9 and 114.5 µg/ml, respectively. The data indicate that ceftiofur and cephalothin were extremely active against A. pleuropneumoniae and with minimum MIC values. These drugs are suitable for controlling and treating hemorrhagic pleuropneumonia outbreaks in swine.
doi:10.1292/jvms.10-0339 pmid:20948169 fatcat:h4qwb4ikrjc4fa32e7xr36ptjm