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The etiology of multiple sclerosis (MS) is not known still. Family cases of MS could prove the genetic predisposition for this disease. We describe here rare for Perm Region family history with three cases of MS in one generation which are characterized by significant clinical polymorphism.doi:10.20538/1682-0363-2009-1(2)-103-105 fatcat:emycrkkcujhpvkn7ceo5m7gbvy