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Plasmablastic lymphomas are high-grade lymphomas that usually occur in immune-suppressed patients. Occasionally, they can arise from an underlying haematolymphoid malignancy, termed 'transformed plasmablastic lymphoma'. In this report, we describe a case of chronic lymphocytic leukaemia and plasmablastic lymphoma in an elderly HIV-negative patient.doi:10.4102/sajo.v1i0.8 fatcat:gzlxg5xkobd75aqze6nlqyczna