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An In Vitro Evaluation of Four Types of Drug-Eluting Microspheres Loaded with Doxorubicin
Journal of Vascular and Interventional Radiology
Purpose: To compare in vitro properties of 4 drug-eluting embolic agents loaded with doxorubicin. Materials and Methods: DC Bead (100-300 mm), LifePearl (200 mm), HepaSphere (30-60 mm), and Tandem (100 mm) microspheres were loaded with 40 mg/20 mL of doxorubicin per milliliter of microspheres. Loading, elution, diameter changes after loading, changes in the amount of doxorubicin loaded over 2 weeks in storage, and time in suspension were evaluated. Results: All microspheres loaded 4 99%doi:10.1016/j.jvir.2016.05.015 pmid:27402527 fatcat:ttxs23wm4nfm5fuyhbutv672zy