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A22-year-old Japanese mandeveloped polyarthritis with fever and urethritis. He was diagnosed as Reiter's syndrome since he was found to have uveitis and persistent aseptic pyuria. Although, he was negative for HLA-B27or any other HLA-B27cross-reactive MHCclass I antigens, he was positive for HLA-B51. The laboratory examination showed significant elevation of serum IgG and IgA anti-Chlamydia antibodies. He was successfully treated with a combination of doxycycline, naproxen, salazosulfapyridinedoi:10.2169/internalmedicine.39.182 fatcat:rtuy63qdxffvflkwavz3p6utxy