Antibacterial Activity Of Anastatica Hierochuntica L. Against Some Bacterial Strains

BENYAGOUB Elhassan, MOGHTET Snoussi, NABBOU Nouria, RAZNI Dalila
2017 Zenodo  
The purpose of this work is to study the biological activity of Anastatica hierochuntica L., against nine bacterial strains responsible of urogenital infection (UTI) for women. The plant was collected from Tindouf region (Far Southwest Algerian). In this study we performed a phytochemical screening and evaluation of antibacterial activity of three macerates of two vegetative parts (seeds and stems) by two methods (disk and wells diffusion method). Given the results, it appears that macerates
more » ... ained were rich in bioactive phyto-constituents particularly the seed of the plant. They showed the presence of ten large chemical groups. The yield of aqueous, methanolic and etheric macerates of the seeds and stems were (5,1; 3,8), (5; 1,4) and (2; 0,95)% respectively. The antibiotic resistance profile of the bacterial strains tested showed an increased resistance against several antibiotics families. The evaluation of the antibacterial potential of macerates showed that methanolic and aqueous macerates of the seeds were more active against Gram-positive bacteria compared to Gram-negative bacteria. The preliminary results of our study, allowed us to predict that natural substances in the plant can be considered as an important source possess compounds with significant antibacterial and antioxidant properties, which suggests their application in the pharmaceutical industry.
doi:10.5281/zenodo.1133717 fatcat:qkd5ebp3drgsxfpa3nve3zxihu