Pre-screening for Osteoporosis with Calcaneus Quantitative Ultrasound and Dual-energy X-ray Absorptiometry Bone Density [post]

Chia-Chi Yen, Wei-Chun Lin, Tzu-Hao Wang, Guan-Fan Chen, Da-Ying Chou, Dian-Min Lin, Shu-Yuan Lin, Min-Ho Chan, Jia-Ming Wu, Chin-Dar Tseng, Yu-Jie Huang, Tsair-Fwu Lee
2020 unpublished
Calcaneal quantitative ultrasonography (QUS) is a useful prescreening tool for osteoporosis, but the advantages of QUS and dual-energy X-ray absorptiometry (DXA) remain unclear. We evaluated the correlation between QUS and DXA in a Taiwanese population. A total of 772 patients were enrolled and demographic data were recorded with the QUS and DXA T-score over the hip and spine. The correlation coefficient of QUS with the DXA-hip was 0.171. For DXA-spine, it was 0.135 overall, 0.237 in females,
more » ... 0.237 in females, and 0.255 in males. The logistic regression model using DXA-spine as a dependent variable was established, and the classification table showed 66.2% accuracy. ROC analyses with Youden's Index revealed the optimal cut-off point of QUS for predicting osteoporosis to be 2.72. This study showed a meaningful correlation between QUS and DXA in a Taiwanese population. Thus, it is important to pre-screen for osteoporosis with calcaneus QUS.
doi:10.21203/rs.3.rs-110965/v1 fatcat:m37bt6leb5hhplfc7krwn6e3ku