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Gene expression analysis of ABC transporter family in breast tumors: relationship with chemotherapy effect and disease prognosis
2020
Uspehi Molekulârnoj Onkologii
Background. One of the main reasons of the ineffectiveness of chemotherapy is still considered to be the formation of the multidrug resistance phenotype of the tumor due to the expression of energy-dependent proteins of ABC transporters. Our previous studies for some ABC genes have established that the expression of these genes correlates with the effectiveness of neoadjuvant chemotherapy (NAC). Some of the clinical studies indicate that ABC transporters can influence not only the formation of
doi:10.17650/2313-805x-2020-7-2-29-38
fatcat:xn5xt5u3rnfzvcs3k5k5acng3i