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Acrokeratoelastoidosis (AKE) and focal acral hyperkeratosis (FAH) are rare genodermatoses with many shared clinical and histopathologically features, distinguished solely by the absence of elastorrhexis in FAH. We present a case of FAH in a 42-year-old woman with HIV-HVB co-infection that showed multiple skin-colored papules with central umbilication on the sides and dorsum of both hands and feet, without nail involvement. Histology showed compact hyperkeratosis with retention ofdoi:10.20431/2456-0022.0201005 fatcat:o34fh5arnreetppmoamgutiqwu