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Insulin-like growth factor 1 (IGF-1) gene plays an important role in bone and soft tumors. IGF-1 gene polymorphisms have been revealed to be correlated with the carcinogenesis and progression of solid malignancies. We therefore hypothesized that IGF-1 genetic polymorphisms might be associated with the risks and outcomes of osteosarcomas in Chinese individuals. Material/Methods: This study included 173 conventional osteosarcoma individuals and 175 tumor-free controls. Five single nucleotidedoi:10.12659/msm.908004 fatcat:4w2ehaofrvaudbznmi3ayj2sai